The debate of mixed versus separate land-use communities still constitutes a controversial matter for different interest groups. A growing number of scholars agree that neighborhoods with mixed compared to separate land-use could achieve sustainable development. On the other hand, residents and practitioners defend neighborhoods with separate land-use where residents can find calm, safety and open greenery spaces. On the other hand' Egyptian authorities fluctuates between promoting and restricting mixed versus separate land-use. Based on a case study in greater Cairo region (Egypt), the research poses to analyze and document the impact of land-use pattern on resident's satisfaction and perception of sustainable development; with reference to their socioeconomic level, and to explore the validity of such impact in Egypt. The case study was selected to be developed by the state and implies open public communities and not including private or gated property, to isolate any missleading satisfaction level. The research found many contradictions and conflicts more than anticipated by literature review, before the start of the research. The research concluded a correlation between resident’s satisfactions to the role of land-use on urban development and their socioeconomic Level. The analyses indicate that high-income residents' satisfaction to living in mixed-use neighborhoods more likely avoided based on key factors of environmental, social, and urban indicators; compared to low income residents' satisfaction, who found living in mixed neighborhoods more highly preferred based on key factors of functional and economic indicators.