Staff Members - Benha University
Plasma alpha glutathione S-Transftease in Chronic Hepatitis C infection in Egypt.
• 1999
Publication Information
Authors
Mahmoud El-Azzouny,Gamal Kenawy, Ibrahim Rageh,Fawzy Magahed, Alaa Ibrahim, Ekram El-Asiouty,Magda Bakr
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Journal
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Pages
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publication.type
Local
Paper Link
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Abstract
Chronic hepatitis C (CHC) infection is a progressive disease whose activity must be regularly assessed. a-Glutathione-S-transferase (a-GST) has been suggested as a better marker of hepatocellular damage than aminotransferases in toxic and autoimmune hepatitis. The present study assessed a-GST as a biochemical marker of hepatocellular damage in 50 Egyptian patients with CHC [seropositive for antihepatitis C virus (HCV) and HCV-RNA]. They were evaluated for conventional liver biochemistry, plasma a-GST, serum HCV -RNA levels and liver biopsy. Plasma aGST was significantly higher in CHC patients than the reference value (P