Staff Members - Benha University
Efficacy of pre-operative silodosin on flexible ureteroscopy procedure: A randomized controlled study
Arab journal of urology • 2023
Publication Information
Authors
Hussein Shaher, Ahmed Sebaey, Ahmed Mahmoud Abd Albaky, Mahmoud Abd Alazeem Mahmoud
and Ashraf Mohammed Abd Elaal
Keywords
Not Available
Journal
Arab journal of urology
Publisher
Not Available
Volume
Not Available
Issue
Not Available
Pages
Not Available
publication.type
International
Paper Link
Open Link
Supplementary Materials
Not Available
Abstract
ABSTRACT
Objectives: To evaluate the impact of silodosin on stages of flexible ureteroscopy (F-URS)
procedures, complications, and stone-free rate (SFR).
Patients and Methods: A prospective, randomized, controlled comparison research was
conducted on 106 patients who were randomly allocated into two groups: the study group
(52 patients) received F-URS with preoperative daily uptake of 8 mg silodosin for 10 days, and
the control group (54 patients) received F- URS without silodosin uptake. Two patients were
lost during the follow up in the study group and four patients were also lost in the controls.
Results: Operative time, application access sheath time (AAST), entrance to ureteric orifice time
(ETUOT), and entrance to bladder time (ETBT) were significantly lower in the study group
compared to controls. Meanwhile, F-URS time & laser time was higher in the study group
compared to controls but without statistically significant difference. Complications were insignificalty different between both studied goups with no impact on SFR.
Conclusion: Before ureteroscopy, silodosin, an adjunctive alpha-blocker therapy, was successful in treating stones resulting in shortening the procedural time, with no impact on SFR or
complication rate.
Objectives: To evaluate the impact of silodosin on stages of flexible ureteroscopy (F-URS)
procedures, complications, and stone-free rate (SFR).
Patients and Methods: A prospective, randomized, controlled comparison research was
conducted on 106 patients who were randomly allocated into two groups: the study group
(52 patients) received F-URS with preoperative daily uptake of 8 mg silodosin for 10 days, and
the control group (54 patients) received F- URS without silodosin uptake. Two patients were
lost during the follow up in the study group and four patients were also lost in the controls.
Results: Operative time, application access sheath time (AAST), entrance to ureteric orifice time
(ETUOT), and entrance to bladder time (ETBT) were significantly lower in the study group
compared to controls. Meanwhile, F-URS time & laser time was higher in the study group
compared to controls but without statistically significant difference. Complications were insignificalty different between both studied goups with no impact on SFR.
Conclusion: Before ureteroscopy, silodosin, an adjunctive alpha-blocker therapy, was successful in treating stones resulting in shortening the procedural time, with no impact on SFR or
complication rate.