Banner

Aluminum Chloride Induced Inflammatory process in Rat’s Brain

Scholars International Journal of Biochemistry • 2020
Back
Publication Information
Authors Hussein A Abdel Maksoud1 , Alshaimaa M Said1*, Mabrouk A Abdeldaiem2 and Mahmoud A. Hassan
Keywords Aluminum chloride, Interleukin, Nervous system, Neurotoxicity, Inflammation, Rat
Journal Scholars International Journal of Biochemistry
Publisher Scholars Middle East Publishers
Volume 3
Issue 10
Pages Not Available
publication.type International
Paper Link Not Available
Supplementary Materials Not Available
Abstract
Neurotoxicity is a form of toxicity in which a biological, chemical, or physical agent produces an adverse effect on the
structure or function of the central and/or peripheral nervous system. This study was conducted to evaluate the neurotoxic
effect of aluminium chloride induced neuroyoxicity in rats. Fourty rats used in this study were divided into two groups:
control group, rats were received normal laboratory diet all over the period of the experiment for 8 weeks and aluminium
chloride protective group received (i.p) injection of AlCl3 daily at dose (300mg/kg). The results revealed that injection of
AlCl3 effected on inflamatory markers where, levels of interleukin (il-2), interleukin-6 (il-6) Tumer Necrosis Factor
(TNF α) were significantly increased