The aim of this study was to investigate some basic and hormonal profiles for selection of short distance swimmers. It is hypothesized that the basic and hormonal profiles of short distance swimmers might help in the sound selection of short distance swimmers in Egypt. The Researcher used the descriptive method for a sample of a high level short distance swimmers participating in the study, from different clubs in Cairo (aged 17.8y) height (176.8 cm), weight (73.8 kg). Basic variables of heart rate, lactate, respiratory rate and vital capacity were determined, together with hormonal profile of growth hormone, testosterone, cortisol, T3, T4 using ELISA technique in the peripheral blood. The results indicated that basic variable determined were better results compared to the average levels of normal person, also the mean hormones were exceeding the average levels of normal concentrations. It may be concluded that the basic variables (heart rate, lactate, respiratory rate and vital capacity, also metabolic and growth hormone detected might be a good indicators for selection of short distance swimmers in Egypt