Immunohistochemical Evaluation of Bcl-2 Oncoprotein in Buffalo’s Adrenal Gland
• 2013
Publication Information
Authors
Hossam Fouad Attia1*, Gamal Hasan Abdel-Rahman2, Mohamed Abdu Nassan3, and Ahmed AbdelAziz Baiomy4
Keywords
Not Available
Journal
Not Available
Publisher
Not Available
Volume
Not Available
Issue
Not Available
Pages
Not Available
publication.type
International
Paper Link
Open Link
Supplementary Materials
Not Available
Abstract
The present study was undertaken to correlate the immunohistochemical expression of Bcl-2 oncoprotein in
buffalo’s adrenal gland in the young and old ages. Paraffin-embedded sections from the adrenal glands representing
the young and old ages were immunostained for Bcl-2 oncoprotein.
A higher percentage of Bcl-2 immunoreactivity was detected in the adrenal cortical cells of the buffaloes at young
ages. The immunoreactivity was moderate in the adrenal cortical cells of the old ages. The degree of intensity was
prominent in the zona reticularis than that of the other zones, while negative immunoreactivity in the cells of the
adrenal medulla.
In conclusion, the immunohistochemical expression of Bcl-2 oncoprotein in the young buffalo’s adrenal gland
(antiapoptotic gene) was prominent than the old ages. So the incidence of apoptosis was prominent in the adrenal
gland cortical cells of the old age than that the adrenal gland cortical cells of the young ages.
buffalo’s adrenal gland in the young and old ages. Paraffin-embedded sections from the adrenal glands representing
the young and old ages were immunostained for Bcl-2 oncoprotein.
A higher percentage of Bcl-2 immunoreactivity was detected in the adrenal cortical cells of the buffaloes at young
ages. The immunoreactivity was moderate in the adrenal cortical cells of the old ages. The degree of intensity was
prominent in the zona reticularis than that of the other zones, while negative immunoreactivity in the cells of the
adrenal medulla.
In conclusion, the immunohistochemical expression of Bcl-2 oncoprotein in the young buffalo’s adrenal gland
(antiapoptotic gene) was prominent than the old ages. So the incidence of apoptosis was prominent in the adrenal
gland cortical cells of the old age than that the adrenal gland cortical cells of the young ages.
Staff Members - Benha University