Rabbit retinal function after Nd –YAG laser treatment
International Journal of chemical and biomedical science • 2015
Publication Information
Authors
Mona Salah Eldin Talaat1, Samira Mohamed Sallam, Sohair El Sayed Negm , Fatma Mohamed Metawe, Horia Fawzy Khatab
Keywords
Rabbet Eyes,
Nd-YAG Laser,
Electroretinogram (ERG)
Journal
International Journal of chemical and biomedical science
Publisher
nternational Journal of chemical and biomedical science
Volume
1(4)
Issue
Not Available
Pages
89-93
publication.type
International
Paper Link
Open Link
Supplementary Materials
Not Available
Abstract
The aim of this work is to test the functional state of the eye retina exposed to
neodymium yag (Nd:YAG) laser beam of the same intensity and duration as that used
in lens posterior capsulotomy after cataract surgery. Rabbits’ eyes were exposed to laser
beam(1064nm, 0.01w/cm
2
and exposuretime of 0.25 sec and 0.1 sec).Changes in the
bioelectricity of the retina were investigated. The experiments were performed on light
and dark adapted eyes of rabbits for control and afterNd:YAGlaserexposure.
Theelectroretinogram; ERGwas recordedin both cases of dark and lightadaption. We
tried to adapt the physical conditions surrounding the exposed eye during laser
exposureand during the measurements. The ERG response was found to be reduced by
about 50%. Selected a-wave & b-wave of the recordedERG signal,before and after
exposure, were measuredin case of laser exposure times 0.25 sec, 0.1 sec in case of
dark and light adaptation. The obtained results indicated a significant reductionin the a-
wave& b-wave amplitudes, more significantly in case of the longer exposure time.
This reduction after treatment, made slow recovery after 4 days and approached to its
control values after 8 days of exposure. The late effect studies indicated a faster
recovery for the shorter exposure time.
neodymium yag (Nd:YAG) laser beam of the same intensity and duration as that used
in lens posterior capsulotomy after cataract surgery. Rabbits’ eyes were exposed to laser
beam(1064nm, 0.01w/cm
2
and exposuretime of 0.25 sec and 0.1 sec).Changes in the
bioelectricity of the retina were investigated. The experiments were performed on light
and dark adapted eyes of rabbits for control and afterNd:YAGlaserexposure.
Theelectroretinogram; ERGwas recordedin both cases of dark and lightadaption. We
tried to adapt the physical conditions surrounding the exposed eye during laser
exposureand during the measurements. The ERG response was found to be reduced by
about 50%. Selected a-wave & b-wave of the recordedERG signal,before and after
exposure, were measuredin case of laser exposure times 0.25 sec, 0.1 sec in case of
dark and light adaptation. The obtained results indicated a significant reductionin the a-
wave& b-wave amplitudes, more significantly in case of the longer exposure time.
This reduction after treatment, made slow recovery after 4 days and approached to its
control values after 8 days of exposure. The late effect studies indicated a faster
recovery for the shorter exposure time.
Staff Members - Benha University