Chest pain is the 2nd most frequent reason for consultation in hospital, especially in emergency department. Aim of the work: The aim of this study was Psychiatric assessment of patients complaining of chest pain and comparison between psychiatric manifestation of patients with unexplained chest pain and those of coronary artery stenosis. Patients and Methods: In this cross-sectional study, consecutive patients were invited from those who seeking care for a chief complaint of chest pain and undergoing coronary angiography at the Benha Cardiology Catheter Unit. Patients with a previous history of organic heart disease, psychiatric disorder or clinical suspicious of Musculoskeletal, esophageal, gastric or pulmonary disease were excluded. A final sample of 200 patients was subjected to: 1- Medical assessment and required investigations to exclude other causes of chest pain. 2- Cardiac catheter and coronary angiograph. Patients were divided into normal (unexplained chest pain, N group) defined as epicardial coronary artery stenosis