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Evaluation of Serum Autotaxin as a Novel Noninvasive Marker for Assessment of Hepatic Fibrosis in Chronic Hepatitis C Patients

Journal or Medical Science And Clinical Researcb • 2016
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Publication Information
Authors Mahmoud A. AI-Azoony Jehan H.Sabry2, Hisham A. Issa3 , Maha Z. Omar Abdelmoneam Ahmed5 , Doaa M. Abd Almoneim6
Keywords Not Available
Journal Journal or Medical Science And Clinical Researcb
Publisher Not Available
Volume Not Available
Issue Not Available
Pages Not Available
publication.type International
Paper Link Not Available
Supplementary Materials Not Available
Abstract
Hepatitis C is a major health problem. Chronic
hepatitis C is a slowly progressive inflammatory
disease which can lead to cirrhosis with all its
complications [lJ. In Egypt, the prevalence rate
reaches 15% in rural areas, with some age groups
suffering from prevalence rates up to 50%. 13.6%
of volunteer blood donors have anti-HCV
antibodies, this high seropositive rate among
Egyptians is about 35 folds higher than other
. countries [21.
Liver fibrosis is the excessive accumulation of
extracellular matrix proteins including collagen
that results from chron ic damage to the liver [3].
The assessment of the stage of liver fibrosis is
esseptial for prognosis and for deciding on
antiviral treatment [4].