Evaluation of Serum Autotaxin as a Novel Noninvasive Marker for Assessment of Hepatic Fibrosis in Chronic Hepatitis C Patients
Journal or Medical Science And Clinical Researcb • 2016
Publication Information
Authors
Mahmoud A. AI-Azoony Jehan H.Sabry2, Hisham A. Issa3
, Maha Z. Omar
Abdelmoneam Ahmed5
, Doaa M. Abd Almoneim6
Keywords
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Journal
Journal or Medical Science And Clinical Researcb
Publisher
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Volume
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Issue
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Pages
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publication.type
International
Paper Link
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Supplementary Materials
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Abstract
Hepatitis C is a major health problem. Chronic
hepatitis C is a slowly progressive inflammatory
disease which can lead to cirrhosis with all its
complications [lJ. In Egypt, the prevalence rate
reaches 15% in rural areas, with some age groups
suffering from prevalence rates up to 50%. 13.6%
of volunteer blood donors have anti-HCV
antibodies, this high seropositive rate among
Egyptians is about 35 folds higher than other
. countries [21.
Liver fibrosis is the excessive accumulation of
extracellular matrix proteins including collagen
that results from chron ic damage to the liver [3].
The assessment of the stage of liver fibrosis is
esseptial for prognosis and for deciding on
antiviral treatment [4].
hepatitis C is a slowly progressive inflammatory
disease which can lead to cirrhosis with all its
complications [lJ. In Egypt, the prevalence rate
reaches 15% in rural areas, with some age groups
suffering from prevalence rates up to 50%. 13.6%
of volunteer blood donors have anti-HCV
antibodies, this high seropositive rate among
Egyptians is about 35 folds higher than other
. countries [21.
Liver fibrosis is the excessive accumulation of
extracellular matrix proteins including collagen
that results from chron ic damage to the liver [3].
The assessment of the stage of liver fibrosis is
esseptial for prognosis and for deciding on
antiviral treatment [4].
Staff Members - Benha University