Evaluation of some hepatoprotective preparations in experimentally induced hepatopathy in Baladi goats
Benha Veterinary Medical Journal • 2020
معلومات البحث
المؤلفون
Rania R. Emam, Mohamed M. Ghanem, Yassein M. Abdel-Raof, Heba M. El-khaiat
الكلمات المفتاحية
Not Available
المجلة العلمية
Benha Veterinary Medical Journal
الناشر
Not Available
المجلد
38
العدد
2
الصفحات
17-25
publication.type
Local
رابط البحث
Not Available
المواد المرفقة
Not Available
الملخص
This work aimed to evaluate the hepatoprotective effect of garlic oil extract and artichoke
extract with regarding to clinical, hematobiochemical alteration and oxidative stress status of
induced acute hepatopathy in Baladi goats. Fifteen Baladi goats were kept for experimental
induction of hepatopathy that treated orally with 0.3 ml /kg of carbon tetrachloride (CCl4)
once and divided randomly into 3 groups each of five. Group A was kept as control positive.
Group B and Group C were treated by garlic oil extract in dose 0.8mg/kg and artichoke
extract in dose 10mg/kg for 15 days for hepatic protection before induction. Clinical and
hematobiochemical examination were carried out at 1st, 3rd and 7th day after induction.
Clinical examinations of CCl4 treated group at first day showed dullness, inappetence, pale
mucous membranes, elevated body temperature and pulse rate and nervous manifestations.
While garlic and artichoke extracts treated groups showed less severe clinical signs that
began to disappear at 3rd day after induction. With the Hematobiochemical examination, the
induced acute hepatopathy group showed significant (P
extract with regarding to clinical, hematobiochemical alteration and oxidative stress status of
induced acute hepatopathy in Baladi goats. Fifteen Baladi goats were kept for experimental
induction of hepatopathy that treated orally with 0.3 ml /kg of carbon tetrachloride (CCl4)
once and divided randomly into 3 groups each of five. Group A was kept as control positive.
Group B and Group C were treated by garlic oil extract in dose 0.8mg/kg and artichoke
extract in dose 10mg/kg for 15 days for hepatic protection before induction. Clinical and
hematobiochemical examination were carried out at 1st, 3rd and 7th day after induction.
Clinical examinations of CCl4 treated group at first day showed dullness, inappetence, pale
mucous membranes, elevated body temperature and pulse rate and nervous manifestations.
While garlic and artichoke extracts treated groups showed less severe clinical signs that
began to disappear at 3rd day after induction. With the Hematobiochemical examination, the
induced acute hepatopathy group showed significant (P
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