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Risk of Ischemic Heart Disease in Patients with Non-alcoholic Fatty Liver Disease

Afro-Egypt J Infect Endem Dis • 2018
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Publication Information
Authors Mostafa Soliman Elkady1 , Hatem Samir Abd El-Raouf1 , Hany Ragheb Elkholy1 , Badawy Abdul Khalek Abdul Aziz1 , Wael Ahmed Maklad2 , Ahmed Abd El-Allah Turkey3 , Hayam Abd EL-Hameed El-sayed1
Keywords Fatty liver-Ischemic Heart disease - Metabolic syndrome
Journal Afro-Egypt J Infect Endem Dis
Publisher Zagazig University
Volume 8
Issue 1
Pages 41-47
publication.type Local
Paper Link Open Link
Supplementary Materials Not Available
Abstract
Background and study aim: Nonalcoholic fatty liver disease (NAFLD) has
an increasing prevalence worldwide. It
has also been closely associated with obesity
and metabolic syndrome - two conditions
known to be associated with ischemic
heart disease (IHD). The aim of this study
was to assess the association between
NAFLD and ischemic heart disease.
Subjects and Methods: 140 patients with
NAFLD and 70 non-NAFLD subjects
were selected. Full history taking, clinical
examination and laboratory tests including
blood sugar, lipid profile and liver profile
were done. Ultrasonography was performed
to prove NAFLD while ECG and echocardiography were used for detection of
myocardial ischemia.
Results: Of the NAFLD group, the
frequency of mild, moderate and severe
NAFLD was 42.9%, 30% and 27.1%
respectively. Subjects with NAFLD had a
significantly higher BMI, waist
circumference and weight compared to those
of non NAFLD group (p=0.014, 0.0218
and