This study was done in Ismailia canal .We chosen five sites to be studied, which have discharge from nearby factories so these sites were characterized by industrial pollution with either heavy metals and/or pesticide. Our study occur in two parts: part I determinations of physicochemical parameters in water and presences of heavy metal and pesticides in water. Part II: using different method for treating the polluted water to remove the pollutants. The result showed that there were no changes on Physicochemical parameter of polluted water before and after treatment. Cadmium, lead, iron and manganese present in different sites with different level. Some pesticide (Deltamethrin, Nicotine, Cyprodinil and Diazinon) present but not at all sites. The biological method ranked superior followed by chemical method then conventional method. Key word: Heavy metal, pesticide, chemical precipitation, bioremediation