Little is known about the use of coping intervention program which based on integrated care pathway (ICP) for mothers and their children with type1 diabetes mellitus. Although parents of those children may experience stressful and difficult conditions, their participation in diabetes management has considered as an important indicator of positive health outcomesand positive coping.Aim: was to assess maternal coping intervention program based on integrated care pathway and its effect on glycemic control of their children with type1diabetes mellitus. Design: A quasi-experimental research was used. Setting: Diabetes Follow-up Clinic, Pediatrics Department at Benha University Hospital.Sample:Purposive sample of 50 mothers and their children with type1diabetes mellitus.Tools:Toolone;an interview questionnaireto gather relevant data to the study(characteristicsof sample and their knowledge regarding diabetes mellitus), Tooltwo;Way of Coping Scale andToolthree; Diabetic Self Care Activities Questionnaire. Results:There were highly statistical significant differences between mothers' coping and their characteristics, knowledge and children's glycemic control. Conclusion: Thecurrent study concluded that the ICP intervention program was effective in improving coping patterns for mothers of children with type1 diabetes mellitus post-program intervention.Recommendations:Coping intervention program based on integrated care pathway should be held formothers of diabetic children to control their glycemic condition.