Breast cancer is one of the main problems related to women's health, and the various forms of treatment can lead to bodily changes and significantly alter women's sexuality and psychological status. Aim: The aim of this study was to evaluate the effect of nursing counseling guided by BETTER model on sexuality, marital Satisfaction and psychological status among breast cancer women. Design: A quasi-experimental research design. Setting: The study was conducted at an Outpatient clinic, Oncology Institute, Menoufia University - Egypt. Sampling: A purposive sample, composed of 87 women was recruited in the study. Tools: Six tools were used for data collection a) A Structured interviewing questionnaire b) Female sexual function index (FSFI) c) Body image scale d) ENRICH marital satisfaction scale E) Tylor anxiety scale (Arabic version) f) Perceived stress scale (PSS). The results: This study showed that there was a highly significant difference at study participants sexuality, marital satisfaction and psychological status pre and post application of nursing counseling guided by BETTER model. Conclusion: Application of nursing counseling guided by BETTER model had high significant impact on improving sexuality, marital satisfaction and psychological status of breast cancer women undergoing treatment. Recommendation: Adopt a BETTER sexual model of counseling for management of sexual dysfunction and psychological problems in breast cancer institutions. Ongoing education for maternity nurses on the impact of breast cancer treatment on women's sexuality and psychological status, as well as strategies to address women's sexual and psychological problems