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Endothelial dysfunction marker YKL-40 is elevated in male patients with idiopathic infertility

• 2018
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Publication Information
Authors S. M. Hanafy1 | H. H. Sabry1 | J. H. Sabry2 | A. M. Hamed1
Keywords endothlial dysfunction, infertility, metabolic syndrome, YKL-40
Journal Not Available
Publisher Not Available
Volume Not Available
Issue Not Available
Pages Not Available
publication.type International
Paper Link Not Available
Supplementary Materials Not Available
Abstract
Metabolic syndrome represents a collection of cardiovascular risk factors, including
overweight, hypertension, dyslipidemia and impaired glucose metabolism, with insulin
resistance. In recent years, the potential relationship between metabolic syndrome
and male factor infertility has been studied. As endothelial dysfunction is the hallmark
of metabolic syndrome, the aim of this work was to assess serum levels of YKL-40
as
a marker of endothelial dysfunction in male patients with idiopathic infertility. The
study revealed that YKL-40
levels were elevated in patients than controls denoting
that endothelial dysfunction might play a role in the pathogenesis of idiopathic infertility
and that YKL-40
as a marker of endothelial dysfunction could be a useful marker of
idiopathic infertility.