Staff Members - Benha University
Noxiousness Valuation of Two Pharmaceutical Plants on White Garden Snail and Their Side Influences on Biochemical Parameters and Histopathological Changes in Brown Rat
Journal of Biobased Materials and Bioenergy • 2022
Publication Information
Authors
Ghada R. Mohamed1, Nevin Ahmed1 2 ∗, Rokayya Sami3 ∗, Ahmed M. A. Mansour4, Nibal A. Hassan5,Nada Benajiba6, and Moamen A. Elbath1
Keywords
Theba pisana, Rattus norvegicus, Abrus precatorius, Ricinus communis.
Journal
Journal of Biobased Materials and Bioenergy
Publisher
Not Available
Volume
16
Issue
Not Available
Pages
138–145
publication.type
International
Paper Link
Not Available
Supplementary Materials
Not Available
Abstract
The current study aimed to evaluated the toxicity of Abrus precatorius (AP) and Ricinus communis
(RC) plants on land snail (Theba pisana) and their effects on biochemical and histological changes
in brown rat (Rattus norvegicus). Different concentration (1%, 1.5%, 2% and 2.5%) of AP and RC
were used in this study to evluate their effects. The findings of this study pertained that the seeds
of AP and RC had potential impact to control T. pisana and the LC50 of AP and RC had negative
effects on many life cycle stages of T. pisana. The oviposition and new generation of T. pisana
decreased by 81.2% and 62.5% and by 100% and 96.7%, while the infertility rate declined by 96.4%
and 82.4% after treating T. pisana by AP and RC, respectively. Results also showed that AP and
RC had weak influences on the liver, spleen, intestine, kidney and testis tissues of R. norvegicus.
Furthermore, the effect was relatively higher for A. precatorius than R. communis on R. norvegicus males
(RC) plants on land snail (Theba pisana) and their effects on biochemical and histological changes
in brown rat (Rattus norvegicus). Different concentration (1%, 1.5%, 2% and 2.5%) of AP and RC
were used in this study to evluate their effects. The findings of this study pertained that the seeds
of AP and RC had potential impact to control T. pisana and the LC50 of AP and RC had negative
effects on many life cycle stages of T. pisana. The oviposition and new generation of T. pisana
decreased by 81.2% and 62.5% and by 100% and 96.7%, while the infertility rate declined by 96.4%
and 82.4% after treating T. pisana by AP and RC, respectively. Results also showed that AP and
RC had weak influences on the liver, spleen, intestine, kidney and testis tissues of R. norvegicus.
Furthermore, the effect was relatively higher for A. precatorius than R. communis on R. norvegicus males