The High Aswan Dam has been constructed during the sixties to protect Egypt from high flood hazards and to provide the required water demand during low flood years. Due to the dam construction and lake formation, the flow downstream the dam has become more controlled and the suspended sediment concentration peaks have been reduced significantly and deposited upstream the dam. These deposited sediments are affecting the storage capacity of the lake by reducing the storage capacity of the lake. This paper is an attempt to predict the future deposition in the Aswan High Dam Reservoir, in order to estimate the effective life span of the reservoir. A numerical model (Delft3D) was implemented to simulate the sedimentation along the reservoir. During the course of this study, the calibration and validation of the model for flow and sediment deposition were applied during the period 2010–2012. A good agreement, between the observed and modeled results for the whole domain, was obvious. Confident with the obtained results, the model was further used to predict the sediment deposition in the reservoir during the period 2010–2025.