Staff Members - Benha University
Study of the Helicobacter pylori infection in chronic obstructive pulmonary disease
ecJ • 2016
Publication Information
Authors
Shereef A. Eisa a, Gehan F. Almehy a, Hisham A. Eisa b, Maha Z. Omar c,
Tarek S. Essawy a, Amal A. Abou Elnass
Keywords
Not Available
Journal
ecJ
Publisher
GEHAN FAROUK
Volume
Not Available
Issue
Not Available
Pages
Not Available
publication.type
International
Paper Link
Not Available
Supplementary Materials
Not Available
Abstract
Abstract Background: COPD may be associated with other systemic diseases including cardiovascular
diseases, diabetes, osteoporosis and peptic ulceration and Helicobacter pylori infection seems
to be the main cause of PUD.
Aims: The aim of this work is to study the association of H. pylori infection in chronic obstructive
pulmonary disease (COPD).
Subject and methods: This study was performed on 80 subjects. They were classified into two
groups: Group I: 65 COPD patients. Group II: 20 healthy control subjects. COPD was diagnosed
according to the Global Initiative for chronic obstructive pulmonary disease admitted at chest
department of Benha University Hospital.
Results: It shows that seropositivity of anti-H. pylori IgG and anti-CagA IgG was higher in
COPD patients than in controls with a highly statistically significant difference (p =0.009 and
0.047 respectively). Also the IgG level of H. pylori positive cases and CagA positive cases was higher
in the COPD group than in the control group with a highly statistically significant difference
(p= 0.027 and 0.0001 respectively).
Conclusion: The present study suggests that patients with COPD have an increased seroprevalence
of Hp infection.
diseases, diabetes, osteoporosis and peptic ulceration and Helicobacter pylori infection seems
to be the main cause of PUD.
Aims: The aim of this work is to study the association of H. pylori infection in chronic obstructive
pulmonary disease (COPD).
Subject and methods: This study was performed on 80 subjects. They were classified into two
groups: Group I: 65 COPD patients. Group II: 20 healthy control subjects. COPD was diagnosed
according to the Global Initiative for chronic obstructive pulmonary disease admitted at chest
department of Benha University Hospital.
Results: It shows that seropositivity of anti-H. pylori IgG and anti-CagA IgG was higher in
COPD patients than in controls with a highly statistically significant difference (p =0.009 and
0.047 respectively). Also the IgG level of H. pylori positive cases and CagA positive cases was higher
in the COPD group than in the control group with a highly statistically significant difference
(p= 0.027 and 0.0001 respectively).
Conclusion: The present study suggests that patients with COPD have an increased seroprevalence
of Hp infection.