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High-sensitivity C-reactive protein and prediction of thromboembolism in patient with atrial fibrillation

• 2016
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Publication Information
Authors Saad Ammar, Mohamed Gaballah, Hosam eldin Eldesouky, Fathy Swailem
Keywords Not Available
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publication.type Local
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Abstract
Background: The possibility that the association of inflammation with AF and the related
thromboembolic risk could be examined with the use of C-reactive protein(CRP) has
captured the attention of many researchers (Versaci et al., 2002; Boss and Lip 2005;
Watanabe et al., 2005; Guazzi and Arena,2009).
Methods: This study on 100 patients from those referred to transesophageal
echocardiography for cardioversion or assessment of left atrial appendage in AFib with
stroke. All patients were subjected to history taking (Age, DM, HTN, previous stroke, IHD,
PVD). physical examination Resting 12- lead surface ECG. Transthoracic echocardiography
to detect LA diameter, LA area and EF. Transesophageal echocardiography to detect LAA
SEC, thrombus, emptying and filling velocities. Measurement of hs-crp.
Results: demographic and clinical characteristic including DM, and HTN, IHD,SEX has no
significant effect on hs-CRP, but CRP concentration was associated positively with age with
significant difference between examined groups (p = 0.003) and PVD with significant
difference between examined groups ( p = 0.001). hs- CRP concentration was significantly
elevated in patients with prior stroke (p