| publication name | Model Studies Related to Synthesis and 1, 4-Dipolar Cycloaddition Reactions of Mesoionic Heterocycles. |
|---|---|
| Authors | Yvette Abd El-Sayed Issac |
| year | 1999 |
| keywords | |
| journal | |
| volume | Not Available |
| issue | Not Available |
| pages | Not Available |
| publisher | Not Available |
| Local/International | International |
| Paper Link | Not Available |
| Full paper | download |
| Supplementary materials | Not Available |
Abstract
The reaction of 2-(substituted amino) pyridine with reactive malonic acid derivatives provided an extremely facile synthesis of the mesoionic compound 4-oxo-4H-pyrido [1, 2-a] pyrimidin-1-ium-2-olates. N, N′-Disubstituted amidine reacted with diethyl malonate to afford 4-quinolone in a one-pot cyclization and rearrangement (type A/I) of 4- oxopyridiniumolate 6. The latter compound was isolated via a reaction of acyclic amidine with AME's. A cycloaddition reaction of the mesoionic pyrimidine 6 with maleic anhydride ...