Staff Members - Benha University
Novel synthesis of phthalazine derivatives as antimicrobial agents
• 2002
Publication Information
Authors
Yvette Issac, Eman El-Karim, Shafie Donia, Mohamed Behalow
Keywords
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Journal
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Publisher
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Volume
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Issue
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Pages
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publication.type
International
Paper Link
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Supplementary Materials
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Abstract
Reaction of 4-(phenoxathiin-2-yl)-1-oxy or mercaptophthalazines 2a, c with phthalyl or
tosylamino acids 3 and 4 has been found to yield 5, 6a-j. Hydrazinolysis of 5, 6a-e furnished
amino derivatives 5, 6k-o. Some of the newly synthesized products were tested for their
antimicrobial activities.
tosylamino acids 3 and 4 has been found to yield 5, 6a-j. Hydrazinolysis of 5, 6a-e furnished
amino derivatives 5, 6k-o. Some of the newly synthesized products were tested for their
antimicrobial activities.