Staff Members - Benha University
Arginine dimethylation products in pediatric patients with chronic kidney disease
Annals of Medicine and Surgery • 2016
Publication Information
Authors
Enas A.A. Abdallah Akram E. El-Sadekcorrespondenceemail , Eman G. Behery , Ahmed A. Azab , Naglaa M. Kamal , Mostafa A. Salama , Waleed E. Abdulghany
Keywords
Not Available
Journal
Annals of Medicine and Surgery
Publisher
Not Available
Volume
9
Issue
Not Available
Pages
22-27
publication.type
International
Paper Link
Not Available
Supplementary Materials
Not Available
Abstract
Background
arginine and its metabolites have been linked to pediatric chronic kidney disease (CKD). We aimed to estimate serum levels of argninine (Arg), asymmetric dimethylarginine (ADMA) and symmetric dimethylarginine (SDMA) in pediatric CKD patients and its relation to altered kidney function.
Patients and methods
132 pediatric patients with CKD and 120 healthy age and sex matched controls were compared regarding; serum Arg, ADMA and SDMA levels.
Results
In comparison to their values in control subjects, serum Arg levels were significantly lower; serum ADMA levels were non-significantly higher, but serum SDMA levels were significantly higher in CKD patients (p values: < 0.000; = 0.054;
arginine and its metabolites have been linked to pediatric chronic kidney disease (CKD). We aimed to estimate serum levels of argninine (Arg), asymmetric dimethylarginine (ADMA) and symmetric dimethylarginine (SDMA) in pediatric CKD patients and its relation to altered kidney function.
Patients and methods
132 pediatric patients with CKD and 120 healthy age and sex matched controls were compared regarding; serum Arg, ADMA and SDMA levels.
Results
In comparison to their values in control subjects, serum Arg levels were significantly lower; serum ADMA levels were non-significantly higher, but serum SDMA levels were significantly higher in CKD patients (p values: < 0.000; = 0.054;