Staff Members - Benha University
Impacts of Macleaya cordata on Productive Performance, Expression of Growth-Related Genes, Hematological, and Biochemical Parameters in Turkey
Frontiers in Veterinary Science • 2022
Publication Information
Authors
Eman A. Manaa, Mervat A. Abdel-Latif , Samya E. Ibraheim, Abdelaziz Sakr , Mahmoud Dawood, Ghadeer M. Albadrani
, Attalla F. El-kott ,Mohamed M. Abdel-Daim and Basant M. Shafik
Keywords
Macleaya cordata, growth performance, gene expression, Sangrovit®, Turkey
Journal
Frontiers in Veterinary Science
Publisher
FRONTIERS MEDIA SA
Volume
Volume 9
Issue
Not Available
Pages
Not Available
publication.type
International
Paper Link
Open Link
Supplementary Materials
Not Available
Abstract
Macleaya cordata (M. cordata) is a herbal plant that has abundant amounts of
sanguinarine, which has many biomedical properties. The effects of M. cordata dietary
supplementation on the productive performance, some blood constituents, and growthrelated genes’ expression were evaluated in turkey. M. cordata extract was dietary
supplemented to turkey at levels of 25, 50, and 100 ppm and a control group. Growth
performance measurements (FBW, ADG, and FCR) and production efficiency factor for
turkey (BPEF) were similar (p > 0.05) in all supplemented groups. M. cordata has no
adverse effects (p > 0.05) on the birds’ health regarding hematological (Hb, RBCs,
WBCs, and PCV) and blood biochemical indices evaluating liver function, kidney function,
and lipid profile. Moreover, the mRNA expression of growth-related genes, such as
growth hormone receptor (GHR), insulin-like growth factor 1 (IGF-1), cyclooxygenase
3 (COX-3), adenine nucleotide translocase (ANT), and uncoupling protein 3 (UCP-3)
were upregulated (p < 0.001) in M. cordata treatments with the highest value for SG50
compared with the control group. We concluded that exogenous M. cordata dietary
supplementation upregulated the expression of growth-related genes in turkey at a level
of 50 ppm without adverse effects on their health status regarding hematological and biochemical indices.
sanguinarine, which has many biomedical properties. The effects of M. cordata dietary
supplementation on the productive performance, some blood constituents, and growthrelated genes’ expression were evaluated in turkey. M. cordata extract was dietary
supplemented to turkey at levels of 25, 50, and 100 ppm and a control group. Growth
performance measurements (FBW, ADG, and FCR) and production efficiency factor for
turkey (BPEF) were similar (p > 0.05) in all supplemented groups. M. cordata has no
adverse effects (p > 0.05) on the birds’ health regarding hematological (Hb, RBCs,
WBCs, and PCV) and blood biochemical indices evaluating liver function, kidney function,
and lipid profile. Moreover, the mRNA expression of growth-related genes, such as
growth hormone receptor (GHR), insulin-like growth factor 1 (IGF-1), cyclooxygenase
3 (COX-3), adenine nucleotide translocase (ANT), and uncoupling protein 3 (UCP-3)
were upregulated (p < 0.001) in M. cordata treatments with the highest value for SG50
compared with the control group. We concluded that exogenous M. cordata dietary
supplementation upregulated the expression of growth-related genes in turkey at a level
of 50 ppm without adverse effects on their health status regarding hematological and biochemical indices.