Staff Members - Benha University
Hypovitaminosis D in patients with Ankylosing Spondylitis: Frequency and Consequences
Current Rheumatology Reviews • 2021
Publication Information
Authors
Gehan Elolemy1 M.D. [The corresponding author]
Waleed Hassan1 M.D.
Mohamed Nasr2 M.D.
Eman Baraka1
Keywords
Not Available
Journal
Current Rheumatology Reviews
Publisher
Not Available
Volume
Not Available
Issue
Not Available
Pages
Not Available
publication.type
International
Paper Link
Not Available
Supplementary Materials
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Abstract
Abstract
Objectives: was to assess the frequency of hypovitaminosis D in patients with ankylosing
spondylitis (AS) compared to healthy controls and to evaluate its association with disease
activity, structural damage and bone mineral density (BMD). Methods: Serum 25(OH) D in 30
AS male patients was compared to 30 matched healthy controls. AS disease activity was
assessed using AS Disease Activity Score and C - reactive protein (ASDAS-CRP). Bath AS
Functional Index (BASFI) and Bath AS Metrology Index (BASMI) were used to assess the
functional impairment and the spinal mobility respectively. Radiological damage was scored
according to modified Stoke AS Spine Score (mSASSS) and BMD was measured in the lumbar
spine and femoral neck. Results: The mean serum 25(OH)D levels in AS patients were
significantly lower compared to healthy controls (27.73 ± 14.27 vs. 38.46 ± 8.11ng/ml, P
Hypovitaminosis D in Ankylosing Spondylitis
2
Objectives: was to assess the frequency of hypovitaminosis D in patients with ankylosing
spondylitis (AS) compared to healthy controls and to evaluate its association with disease
activity, structural damage and bone mineral density (BMD). Methods: Serum 25(OH) D in 30
AS male patients was compared to 30 matched healthy controls. AS disease activity was
assessed using AS Disease Activity Score and C - reactive protein (ASDAS-CRP). Bath AS
Functional Index (BASFI) and Bath AS Metrology Index (BASMI) were used to assess the
functional impairment and the spinal mobility respectively. Radiological damage was scored
according to modified Stoke AS Spine Score (mSASSS) and BMD was measured in the lumbar
spine and femoral neck. Results: The mean serum 25(OH)D levels in AS patients were
significantly lower compared to healthy controls (27.73 ± 14.27 vs. 38.46 ± 8.11ng/ml, P
Hypovitaminosis D in Ankylosing Spondylitis
2