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The Effect of Hemodynamically Significant Patent Ductus Arteriosus on Necrotizing Enterocolitis and Cerebral Changes in Preterm Infants

• 2023
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Publication Information
Authors Eman G.Abdel Rahman1, Asmaa El falah2, Mariam Hamdy Afifi 3,Safa Elsayed Elazab1* Omima Mohamed Abdel Haie1 Wesam E. Afifi1
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publication.type International
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Abstract
Background: Hemodynamically significant PDA (HSPDA) is associated with increased mortality and several significant morbidities including necrotizing enterocolitis (NEC), cerebral ischemia, intraventricular hemorrhage, pulmonary hemorrhage, or bronchopulmonary dysplasia.
The aim of study: was to assess the cerebral hemodynamic changes and NEC in preterm infants diagnosed with HSPDA and to investigate the role of Human Epithelial derived neutrophil chemoattractant-78/ C-X-C Motif Chemokine Ligand 5 (ENA-78/CXCL5) as a diagnostic tool for NEC in HS PDA.
Methods: This prospective case-control research was carried out on preterm infants (GA