Staff Members - Benha University
Association of left atrial deformation indices with left atrial appendage thrombus in patients with non valvular atrial fibrillation
• 2020
Publication Information
Authors
Shaimaa Mostafa*
, Khaled El-Rabbat, Safaa Salah, Eman Elkeishk
Keywords
Not Available
Journal
Not Available
Publisher
Not Available
Volume
Not Available
Issue
Not Available
Pages
Not Available
publication.type
Local
Paper Link
Not Available
Supplementary Materials
Not Available
Abstract
Aim: Assessment of the value of left atrial deformation indices for prediction of left atrial appendage
functioning patients with non-valvular atrial fibrillation.
Method: The study included 250 patients with non-valvular atrial fibrillation and normal left atrial
dimension. Trans-thoracic and trans-esophageal echocardiography were performed. Patients were
divided into two groups; patients with LAA thrombus (group I) and patients without LAA thrombus
(group II), a correlation between trans-esophageal and trans-thoracic data was analyzed.
Results: Group I included110 patients (44%) and Group II 140 patients (56%). By TDI mean LA strain and
strain rate were lower in group I (21.89 ± 7.75% vs 35.14 ± 9.28%; p < 0.001) and (1.15/sec, IQR 0.12e3/sec
versus 2.1/sec, IQR 0.21e3/sec, p < 0.001) respectively. By speckle tracking PALS and strain rate were
lower in group I (24.79 ± 7.78% vs 37.63 ± 8.64%; p value < 0.001) and (0.95 ± 0.32/sec. Vs 1.27 ± 0.32/sec
p, value < 0.001) respectively. By TEE; group I had lower LAA EF (39.2 ± 13.55% vs 53.86 ± 12.7%);
p < 0.001, and lower LAA emptying velocity (17.53 cm/s, IQR 9.54e77.4 vs 63.5 cm/s, IQR 7.89e86.4;
p < 0.001). There was a good correlation between LA TDI and speckle tracking PALS and PALSR and LAA
EF% and velocity p < 0.001. TDI and PALS and PALSR were found to be significant predictors for LAA
thrombus (P < 0.05) with good sensitivity and specificity.
Conclusion: Left atrium deformation indices are predictors of LAA thrombus or SEC in patients with nonvalvular AF with accepted sensitivity and specificity.
© 2020 Cardiological Society of India. Published by Elsevier B.V. This is an open access article under the
functioning patients with non-valvular atrial fibrillation.
Method: The study included 250 patients with non-valvular atrial fibrillation and normal left atrial
dimension. Trans-thoracic and trans-esophageal echocardiography were performed. Patients were
divided into two groups; patients with LAA thrombus (group I) and patients without LAA thrombus
(group II), a correlation between trans-esophageal and trans-thoracic data was analyzed.
Results: Group I included110 patients (44%) and Group II 140 patients (56%). By TDI mean LA strain and
strain rate were lower in group I (21.89 ± 7.75% vs 35.14 ± 9.28%; p < 0.001) and (1.15/sec, IQR 0.12e3/sec
versus 2.1/sec, IQR 0.21e3/sec, p < 0.001) respectively. By speckle tracking PALS and strain rate were
lower in group I (24.79 ± 7.78% vs 37.63 ± 8.64%; p value < 0.001) and (0.95 ± 0.32/sec. Vs 1.27 ± 0.32/sec
p, value < 0.001) respectively. By TEE; group I had lower LAA EF (39.2 ± 13.55% vs 53.86 ± 12.7%);
p < 0.001, and lower LAA emptying velocity (17.53 cm/s, IQR 9.54e77.4 vs 63.5 cm/s, IQR 7.89e86.4;
p < 0.001). There was a good correlation between LA TDI and speckle tracking PALS and PALSR and LAA
EF% and velocity p < 0.001. TDI and PALS and PALSR were found to be significant predictors for LAA
thrombus (P < 0.05) with good sensitivity and specificity.
Conclusion: Left atrium deformation indices are predictors of LAA thrombus or SEC in patients with nonvalvular AF with accepted sensitivity and specificity.
© 2020 Cardiological Society of India. Published by Elsevier B.V. This is an open access article under the