The aim of this study is to investigate the efficacy of WGO and Coenzyme Q10 low and high doses on
physiological performance and testicular oxidative status of male rabbit bucks. In addition tracing the best suitable
interval which modulates physiological response under Egyptian summer condition. This experiment was done
on a pure strain of Sinai gabali bucks 3 months old. The animals were randomly divided into four groups each
one comprise 6 animals. The 1st group served as normal control (C), the 2
nd group treated with wheat germ oil
(WGO) (300 mg/kg BW), the 3
rd group treated with Coenzyme Q10L (10 mg /kg BW), and the 4
th group treated
with Coenzyme Q10H (20 mg/kg BW).Rabbits of all treatments were given oral administration daily for 60 days,
and blood samples were collected monthly along 6 months after the end of the treatment. Moreover, the rabbits
were decapitated and the testes tissues were exceed for evaluation Reduced Glutathione (GSH), Malondialdehyde
(MDA), Oxidized Glutathione (GSSG) and Nitric oxide (NO) contents. Data revealed that liver function did not
show any significant differences due to treatment. Month effect did not show any differences in ALT and AST
values. According to the interaction of treatment and month data showed the best value of ALT and AST (26.48
and 32.72 U/L, respectively) in C× 6th and Coenzyme Q10L ×5
th month, respectively. With regard to Lipid profile
data showed significant decrease (P