Two field experiments were carried out during two successive winter seasons at 2013 and 2014, in a private farm at Abuo-Hammad area, Sharkia Governorate, Egypt, to evaluate the integrated fertilization management i.e. chemical fertilization (NPK), biofertilization (Rhizobium leguminosarum. bv. vicieae, Glomas bagyarajii, Bacillus circulans) with or without foliar applications of yeast extract (Saccharomyces cereviseae) and micronutrients on enzymes activity, nodulation status, growth characteristics, chemical constituents, mycorrhizal infection (%) and yield of pea (Pisum sativum L.) cv. Master B grown under loamy sandy soil conditions. All estimated parameters were affected by biofertilizers application, especially in combination with foliar applied with yeast extract. The highest values of the most studied parameters were recorded in combination between biofertilizers with foliar application of micronutrients and yeast extract.