pre-menopause is an important event through a woman’s life. Women with accurate information about the pre-menopause can be able to manage the associated problems better. Aim: evaluate the effect of an educational package on knowledge, practices, and attitude of premenopausal women regarding sexuality. Design: A quasi-experimental research design of the study was used. Sample: A purposive sample of 80 premenopausal women. Setting: This research was conducted in the obstetrics and gynecology Outpatient Clinic at Fayoum University Hospital. Tools: Two tools have been used to gather data; 1) Structured questionnaire interview sheet 2) Modified Likert scale. Results: The study showed a highly statistically significant difference between pre and post educational package regarding knowledge, practices, and attitude of premenopausal women regarding sexuality. There was a highly significant correlation between total knowledge and total sexual history pre and post educational package. Conclusion: The implementation educational package significantly improved knowledge, practices, and attitude of premenopausal women regarding sexuality. Recommendations: Proper training of health care providers to understand women's attitudes regarding pre-menopause in order to give optimal information and help to create a positive attitude of pre-menopause. Counseling activities of premenopausal, menopausal, and post-menopausal women need to popularize and facilities and decision aids made available to those who need them.