Background: for limiting the spread of COVID-19, the Egyptian government had declared a national lockdown on March 24, 2020 with reduction of all the governmental medical services. Methods: cross sectional study included 263 working ophthalmologists from all across Egypt. They were asked to fill in a questionnaire about the changes in their clinical practice of ophthalmology. The questionnaire was distributed as a Google form through Emails and different social media platforms. Young ophthalmologists (35 years) regarding the use of technology and E-learning during the lockdown of the pandemic. Ophthalmologists with private practice were compared to ophthalmologists without regarding the changes in real-life clinical practice during the same period. Results: The mean age of the participants was 45.6 y (27.0-68 y), 67.3% were males and 52.1% were having private practice either alone or with governmental practice. The majority of the participants (86.7%) were still seeing patients during the lockdown, however, 96.2% of them decreased the number of their working days and 94.3% decreased the number of patients. About 47% of the participants stopped all surgeries, 9.9% performed only emergency surgeries and 42.6% performed any surgery. All the participants wore facial masks, 88.6% used breath shields, 55.5% wore gloves and 59.7% started online consultations. Experienced ophthalmologists significantly attended more scientific webinars but for young ophthalmologists; webinars were very useful medically but not helpful for their surgical skills. 2 Conclusion: the lockdown of COVID-19 did not stop ophthalmological practice in Egypt. It reduced the number of working days and the number of patients. All the participants have used different PPE and half of them started online consultations. E-learning was very useful for young ophthalmologists but it did not help their surgical skills