Background: Checking students’ perception regarding the quality of nursing courses is one of the main items that can help in the educational nursing courses development and improvement to achieve the desired intended learning outcomes and academic achievement. Aim: This study aimed to assess nursing students' perception regarding the quality of nursing courses and its relation to their academic achievement. Research Design: A descriptive correlational research design was utilized to conduct this study. Setting: The study was conducted at Faculty of Nursing-Benha University, Egypt. Sample: Non-probability quota sample consisted of 752 from total 1438 nursing students who were in different academic grades and studied nursing courses in academic year 2015/2016. Tools of data collection: Three tools were employed in this study namely: Personal data of nursing student questionnaire, Quality of nursing courses questionnaire, and auditing checklist of nursing student's academic achievement. Results: The study yield that more than half (57.0%) of the studied nursing students had moderate level of perception regarding the quality of nursing courses, while and minority (10.4%) of them had high level of perception regarding the quality of nursing courses. Also more than half (52.0%) of the studied nursing students were very good in their total academic achievement, and slightly more than one quarter (26.5%) of them were excellent in their total academic achievement. Conclusion: There was a strong positive statistical significant correlation between the studied nursing students' perception regarding the quality of nursing courses and their academic achievement. Recommendations: Nursing students' perception regarding quality of nursing courses should be considered and discussed by academic teaching staff and faculty of nursing administrators to make needed development to motivate the nursing students to attain highly academic achievement. Clarifying the objectives of nursing courses for nursing students and encourage teaching strategy of student-center approach.