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Sequence Analysis of VP1 Gene Foot-and-Mouth Disease Virus Serotype A and O Isolates from Different Governorates in Egypt

Benha Vet. Med. J. • 2011
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Publication Information
Authors El-Bagoury, G.F.; El-Sayed, W. M.; El-Nahas, E.M.; El-Habbaa, A.S.and Azab, A.H
Keywords Not Available
Journal Benha Vet. Med. J.
Publisher Not Available
Volume special
Issue 1
Pages 122-128
publication.type Local
Paper Link Not Available
Supplementary Materials Not Available
Abstract
The nucleotide and deduced amino acid sequences of VP1-coding region of foot-and-mouth disease
viruses (FMDV) serotype A and O, isolated during the recent emergencies of the disease in Egypt (El-
Monofia, kaluobia, Sharkia and Beni suef between the years 2009 and 2010) were determined. A
phylogenetic analysis was performed based on comparison with continental relevant field and vaccinal
strains. The results showed that there was no significant divergence between the isolated strains as the
divergence of the 3 end of the 1D gene was 0.6 to 1.8 % among serotypes A and 0.2 to 1.4% among
serotypes O. When compared with the continental viruses available for the phylogenetic studies, they
showed the closest relationship of serotype A and O isolates with FMDV serotype A / EGY / 2006 and
serotype O /EGY /93 respectively