Ten adult she-camels were used to study histological structure of the vulva and the immunohitochemical localization of estrogen receptor alpha (ERα) and progesterone receptor (PR). Histologically, the vulvar lip consists of mucosal surface, cutaneous surface and connective tissue core. The mucous surface is lined with keratinized stratified squamous epithelium while thecutaneous surface is covered with skin and its appendages except sweat gland. Immunohistochemically, ERα is identified in the epithelia of both surfaces of the vulva but PR is not identified in the skinof vulva of camel. Both ERα and PR are localized in the nuclei of the basal and parabasal cell layers in the vulvar epithelia indicating their role in growth and differentiation.