Introduction: Sexual satisfaction is a multidimensional experience involving thoughts, feelings, personal and sociocultural attitudes and beliefs, combined with biological factors. Aim of the Study: The present study aimed to assess the degree of sexual satisfaction and its predictors in a convenience sample of married Egyptian women. Materials and Methods: 302 married women were recruited for this study. The tool used was a self-report questionnaire designed by the authors with the help of the COSECON survey. The questionnaire included questions about demographic data, sexual satisfaction, sexual activities e.g. frequency of coitus, obtaining lubrication and orgasm. Results: The degree of sexual satisfaction was as follows: 57.9% highly satisfied, 22.2%%moderately satisfied and 19.9% dissatisfied. The main predictors of satisfaction were: age, coital frequency, spontaneous desire, lubrication and the ability to reach orgasm. Foreplay duration and method, duration of marriage, residence and educational level were all related to sexual satisfaction. Conclusion: Sexual medicine counselors may benefit from the present work in dealing with their female clients. Determining the degree of sexual satisfaction plus looking for its predictors are important in helping couples with a problematic sexual relation.