| publication name | EphB2 isolates a human marrow stromal cell subpopulation with enhanced ability to contribute to the resident intestinal cellular pool |
|---|---|
| Authors | Evan Colletti,* Deena El Shabrawy,*,1 Melisa Soland,*, Takashi Yamagami,*,2 Saloomeh Mokhtari,*, Craig Osborne,† Karen Schlauch,‡,§ Esmail D. Zanjani,* Christopher D. Porada,*, and Graça Almeida-Porada*, |
| year | 2017 |
| keywords | Key Words: crypts of Lieberkühn transcriptome Musashi-1 epithelial Lgr5 transplant niche |
| journal | |
| volume | Not Available |
| issue | Not Available |
| pages | Not Available |
| publisher | Not Available |
| Local/International | International |
| Paper Link | Not Available |
| Full paper | download |
| Supplementary materials | Not Available |
Abstract
To identify human bone marrow stromal cell (BMSC) subsets with enhanced ability to engraft/ contribute to the resident intestinal cellular pool, we transplanted clonally derived BMSCs into fetal sheep. Analysis at 75 d post-transplantation showed 2 of the 6 clones engrafting the intestine at 4- to 5-fold higher levels (5.030.089 and 5.040.15%, respectively) than the other clones (P