Sepsis is defined as life threatening organ dysfunction caused by dysregulated host response to infection (Singer et al, 2016).The new definition abandoned use of host inflammatory response syndrome criteria (SIRS) in identification of sepsis. Systemic inflammatory response syndrome (SIRS) criteria include tachycardia, tachypnea, fever or hypothermia, leukocytosis or leucopenia for age. Patients who met two or more of these criteria fulfilled the definition of SIRS, and Sepsis was defined as infection or suspected infection leading to onset of SIRS. Sepsis complicated by organ dysfunction was termed severe sepsis, which could progress to septic shock.(