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Vascular endothelial growth factor and subclinical atherosclerosis by carotid ultrasonography in Egyptian patients with Behc¸ et’s disease

• 2013
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Publication Information
Authors Sahar S. Ganeb a,*, Hanan H. Sabry b, Mohammed M. El-Assal c, Howyda M. Kamal d, Ayser A. Fayed e, Islam M. El-Shazly
Keywords Behc¸ et’s disease; Vascular endothelial growth factor; B-mode ultrasonography; Disease activity
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publication.type International
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Abstract
Aim of the work: This study aimed to investigate serum levels of vascular endothelial
growth factor (VEGF) and to measure common carotid intima media thickness (cc-IMT) in Egyptian
patients with Behc¸ et’s disease (BD) to evaluate their relations to disease activity and different
clinical manifestations.
Patients and methods: Seventy patients with BD and 70 healthy controls participated in this
study. Behc¸ et’s disease patients were subjected to detailed history taking, thorough clinical examination,
disease activity assessment using the BD Current Activity Form (BDCAF) and laboratory
investigation. Vascular endothelial growth factor levels were measured using ELISA. The carotid
arteries were assessed for cc-IMT and plaques with a carotid high-resolution B-mode ultrasound.