Staff Members - Benha University
Obesity,HelicobacterpyloriInfectionandPreeclampsia:AtriangleofDanger forpregnantwome
• 2018
Publication Information
Authors
Ayman
Ahmed
Abdelhamid
Shedid, Ahmed
WalidAnwar
Moura
Keywords
Preeclampsia,Hpyloriinfection,Bodymassindex,Primigravida
Journal
Not Available
Publisher
Not Available
Volume
Not Available
Issue
Not Available
Pages
Not Available
publication.type
International
Paper Link
Not Available
Supplementary Materials
Not Available
Abstract
Objectives:To determine the frequency ofHelicobacterpylori(Hp)infection among
primigravidaanditsrelationtodevelopmentofpreeclampsia(PE)
Patients&Methods:Thiscohortstudyincluded146primigravidaevaluatedpriortothe12th
weekgestationalage,womenwhodevelopedPEwerecategorizedasPEgroupandasimilar
numberofpregnantwomenfreeofhypertensivemanifestationsascontrol(NoPE)group.All
patientswereevaluatedforageandbodymassindex(BMI)andunderwentHpdiagnosis
workupincludingUreabreathtestandHpstoolantigentesting.
Results:Twenty-sixwomendevelopedearlyand47developedlatePEand52hadmild,while
21hadseverePE.DevelopmentandseverityofPEshowedpositivesignificantcorrelation
withBMI.SixtypatientswereHp+;bloodpressuremeasuresattimeofdevelopmentofPE
weresignificantlyhigherinHp+thaninHp-patients,irrespectiveofdevelopingPE.Blood
pressure measures and BMIshowed positive significantcorrelation with Hp positivity.
StatisticalanalysisdefinedhighBMIasthesignificantindependentpredictorfordevelopment
ofPE.
Conclusion:HighBMImayunderliethedevelopmentandseverityofPEandisassociatedwith
Hpinfection
primigravidaanditsrelationtodevelopmentofpreeclampsia(PE)
Patients&Methods:Thiscohortstudyincluded146primigravidaevaluatedpriortothe12th
weekgestationalage,womenwhodevelopedPEwerecategorizedasPEgroupandasimilar
numberofpregnantwomenfreeofhypertensivemanifestationsascontrol(NoPE)group.All
patientswereevaluatedforageandbodymassindex(BMI)andunderwentHpdiagnosis
workupincludingUreabreathtestandHpstoolantigentesting.
Results:Twenty-sixwomendevelopedearlyand47developedlatePEand52hadmild,while
21hadseverePE.DevelopmentandseverityofPEshowedpositivesignificantcorrelation
withBMI.SixtypatientswereHp+;bloodpressuremeasuresattimeofdevelopmentofPE
weresignificantlyhigherinHp+thaninHp-patients,irrespectiveofdevelopingPE.Blood
pressure measures and BMIshowed positive significantcorrelation with Hp positivity.
StatisticalanalysisdefinedhighBMIasthesignificantindependentpredictorfordevelopment
ofPE.
Conclusion:HighBMImayunderliethedevelopmentandseverityofPEandisassociatedwith
Hpinfection