Staff Members - Benha University
Comparative Study of the Efficacy of Combined Sofosbuvir Ribavirin in Treatment Naive versus Treatment Experienced Egyptian Patients with Chronic Hepatitis C
International Journal of Advanced Research • 2016
Publication Information
Authors
Ayman El-Badawy1, Mohamed YehiaSeddek1, Mohamed Shawky El-sayed1 and Azez Mohammed
Bedeer2.
Keywords
Not Available
Journal
International Journal of Advanced Research
Publisher
Not Available
Volume
4
Issue
11
Pages
1081-1087
publication.type
International
Paper Link
Not Available
Supplementary Materials
Not Available
Abstract
We conducted this study to assess the efficacy
of the oral nucleotide polymerase inhibitor sofosbuvir in combination
with ribavirin in Egyptian patients chronically infected with genotype
4 hepatitis C virus (HCV).
Methods: Treatment-naive and previously treated patients
withgenotype 4 HCV were randomly allocated in a 1:1 ratio to receive
sofosbuvir 400 mg and weight-based ribavirin , for 24 weeks. The
primary efficacy endpoint was the proportion of patients with
sustained virologic response (HCV RNA
of the oral nucleotide polymerase inhibitor sofosbuvir in combination
with ribavirin in Egyptian patients chronically infected with genotype
4 hepatitis C virus (HCV).
Methods: Treatment-naive and previously treated patients
withgenotype 4 HCV were randomly allocated in a 1:1 ratio to receive
sofosbuvir 400 mg and weight-based ribavirin , for 24 weeks. The
primary efficacy endpoint was the proportion of patients with
sustained virologic response (HCV RNA