| publication name | Comparative Study of the Efficacy of Combined Sofosbuvir Ribavirin in Treatment Naive versus Treatment Experienced Egyptian Patients with Chronic Hepatitis C |
|---|---|
| Authors | Ayman El-Badawy1, Mohamed YehiaSeddek1, Mohamed Shawky El-sayed1 and Azez Mohammed Bedeer2. |
| year | 2016 |
| keywords | |
| journal | International Journal of Advanced Research |
| volume | 4 |
| issue | 11 |
| pages | 1081-1087 |
| publisher | Not Available |
| Local/International | International |
| Paper Link | Not Available |
| Full paper | download |
| Supplementary materials | Not Available |
Abstract
We conducted this study to assess the efficacy of the oral nucleotide polymerase inhibitor sofosbuvir in combination with ribavirin in Egyptian patients chronically infected with genotype 4 hepatitis C virus (HCV). Methods: Treatment-naive and previously treated patients withgenotype 4 HCV were randomly allocated in a 1:1 ratio to receive sofosbuvir 400 mg and weight-based ribavirin , for 24 weeks. The primary efficacy endpoint was the proportion of patients with sustained virologic response (HCV RNA