أعضاء هيئة التدريس - جامعة بنها
Treatment of Acute Iliofemoral Deep Vein Thrombosis; Does Catheter Directed Thrombolytic Therapy Change Outcomes?
Cardio Open, 2019 • 2019
معلومات البحث
المؤلفون
Ayman M. Fakhry1, El-Sayed A. Abd El-Mabood2,3, Waleed A. Sorour4, Ayman M. Abdelmofeed2, Taher H. Elwan2,5,Ahmed Fouad Ahmed2 Mohamed E. Abd Ellatief 2 and Saied ELMOKKADEM
الكلمات المفتاحية
Iliofemoral venous thrombosis, Catheter-directed
thrombolysis; Standard anticoagulation, Post-thrombotic Syndrome
المجلة العلمية
Cardio Open, 2019
الناشر
www.opastonline.com
المجلد
Volume 4 | Issue 3 | 1 of 11
العدد
Volume 4 | Issue 3 | 1 of 11
الصفحات
Volume 4 | Issue 3 | 1 of 11
publication.type
International
رابط البحث
Open Link
المواد المرفقة
Not Available
الملخص
Background: Iliofemoral deep vein thrombosis (DVT) is associated with severe post-thrombotic morbidity when treated
with anticoagulation alone. Catheter- directed thrombolysis (CDT) allows early removal of thrombus and reduces valvular
reflux and Post-thrombotic Syndrome (PTS).
Patients and methods: This prospective randomized multi-center controlled two- arm blind study was conducted in 6
centers on 252 patients with iliofemoral DVT. Patients were randomly allocated by using simple random allocation cards
method into two groups; Group (A): CDT followed by oral anticoagulation (N=126 (50%)), Group (B): Standard DVT
therapy (N=126 (50%)). Follow-up was for 24 months.
Results: Patients of group (A) significantly complained less pain at 10 & 30 days (P-Value: 0.02 & 0.04 respectively). Also
there was significant decrease in leg circumference in group (A) at 10 & 30 days (P-Value: 0.001 & 0.03 respectively).
Patency of iliac vein segment was significantly higher in group (A) during the 24 months follow up (P-Value
with anticoagulation alone. Catheter- directed thrombolysis (CDT) allows early removal of thrombus and reduces valvular
reflux and Post-thrombotic Syndrome (PTS).
Patients and methods: This prospective randomized multi-center controlled two- arm blind study was conducted in 6
centers on 252 patients with iliofemoral DVT. Patients were randomly allocated by using simple random allocation cards
method into two groups; Group (A): CDT followed by oral anticoagulation (N=126 (50%)), Group (B): Standard DVT
therapy (N=126 (50%)). Follow-up was for 24 months.
Results: Patients of group (A) significantly complained less pain at 10 & 30 days (P-Value: 0.02 & 0.04 respectively). Also
there was significant decrease in leg circumference in group (A) at 10 & 30 days (P-Value: 0.001 & 0.03 respectively).
Patency of iliac vein segment was significantly higher in group (A) during the 24 months follow up (P-Value