| publication name | Treatment of Acute Iliofemoral Deep Vein Thrombosis; Does Catheter Directed Thrombolytic Therapy Change Outcomes? |
|---|---|
| Authors | Ayman M. Fakhry1, El-Sayed A. Abd El-Mabood2,3, Waleed A. Sorour4, Ayman M. Abdelmofeed2, Taher H. Elwan2,5,Ahmed Fouad Ahmed2 Mohamed E. Abd Ellatief 2 and Saied ELMOKKADEM |
| year | 2019 |
| keywords | Iliofemoral venous thrombosis, Catheter-directed thrombolysis; Standard anticoagulation, Post-thrombotic Syndrome |
| journal | Cardio Open, 2019 |
| volume | Volume 4 | Issue 3 | 1 of 11 |
| issue | Volume 4 | Issue 3 | 1 of 11 |
| pages | Volume 4 | Issue 3 | 1 of 11 |
| publisher | www.opastonline.com |
| Local/International | International |
| Paper Link | www.opastonline.com Volume 4 | Issue 3 | 1 of 11 |
| Full paper | download |
| Supplementary materials | Not Available |
Abstract
Background: Iliofemoral deep vein thrombosis (DVT) is associated with severe post-thrombotic morbidity when treated with anticoagulation alone. Catheter- directed thrombolysis (CDT) allows early removal of thrombus and reduces valvular reflux and Post-thrombotic Syndrome (PTS). Patients and methods: This prospective randomized multi-center controlled two- arm blind study was conducted in 6 centers on 252 patients with iliofemoral DVT. Patients were randomly allocated by using simple random allocation cards method into two groups; Group (A): CDT followed by oral anticoagulation (N=126 (50%)), Group (B): Standard DVT therapy (N=126 (50%)). Follow-up was for 24 months. Results: Patients of group (A) significantly complained less pain at 10 & 30 days (P-Value: 0.02 & 0.04 respectively). Also there was significant decrease in leg circumference in group (A) at 10 & 30 days (P-Value: 0.001 & 0.03 respectively). Patency of iliac vein segment was significantly higher in group (A) during the 24 months follow up (P-Value