Staff Members - Benha University
EFFECT OF VACCINE ON THE ROLE OF SHEEP AS A CARRIER FOR TRANSMISSION OF FOOT AND MOUTH DISEASE VIRUS
BENHA VETERINARY MEDICAL JOURNAL • 2012
Publication Information
Authors
G F El-Bagoury, A S El-Habbaa, Amal A. Mohamed and M A Saad
Keywords
ELISA, FMD, Sheep, SNT, Vaccine
Journal
BENHA VETERINARY MEDICAL JOURNAL
Publisher
Faculty of Veterinary Medicine, Benha University, Egypt
Volume
23
Issue
2
Pages
100-107
publication.type
International
Paper Link
Open Link
Supplementary Materials
Not Available
Abstract
Sheep plays an important role as a carrier in the persistence and the spread of Foot and Mouth Disease Virus (FMDV). The ability of high potency inactivated bivalent FMDV (A and O) vaccine to inhibit
local replication of FMDV and carrier state in sheep was studied. The vaccine induced protective titer of serum neutralizing antibody14th days post vaccination and protected vaccinated sheep at challenge after 21 days or 7 months post vaccination in comparison to non-vaccinated one. Oro-pharyngeal fluid
samples collected from vaccinated group of sheep showed absence of FMDV antigen for one month post challenge time using ELISA, conversely to non-vaccinated one which transmitted viral infection to contact calves. Our results reflected the important role of highly potent FMDV vaccine in prevention of the carrier state in sheep
local replication of FMDV and carrier state in sheep was studied. The vaccine induced protective titer of serum neutralizing antibody14th days post vaccination and protected vaccinated sheep at challenge after 21 days or 7 months post vaccination in comparison to non-vaccinated one. Oro-pharyngeal fluid
samples collected from vaccinated group of sheep showed absence of FMDV antigen for one month post challenge time using ELISA, conversely to non-vaccinated one which transmitted viral infection to contact calves. Our results reflected the important role of highly potent FMDV vaccine in prevention of the carrier state in sheep