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publication name Influence of ketamine, thiopental or propofol anaesthesia on acute phase proteins in buffalo calves
Authors Khalid Fararh; Adel Al-Akraa; Atef Abd-Algalil
year 2011
keywords anesthesia; buffalo calves; acute phase protein
journal Egypt. J. Comp. Path &Clinic Path
volume 24
issue 1
pages 155-178
publisher Not Available
Local/International Local
Paper Link Not Available
Full paper download
Supplementary materials Not Available
Abstract

The objective of this study was to compare the changes of acute phase proteins after ketamine, thiopental and propofol anaesthesia in buffalo calves. Five calves were anaesthetized three times with ketamine, thiopental or propofol in random order at 3 weeks intervals. Calves were pre-medicated with xylazine and buterphenol. Propofol resulted in an excellent anaesthetic induction (free of excitement), short recovery times and duration of anaesthesia, whereas ketamine and thiopental produced a good and fair quality of induction respectively. Acute phase proteins showed significant increase in haptoglobin and fibrinogen, whereas albumin was significantly decreased in all groups. Haptoglobin returned to normal values 48 hours after anaesthesia with propofol and thiopental. In conclusion, the anaesthetic quality produced by propofol in buffalo calves was better compared to those of ketamine and thiopental but it has a shortThe objective of this study was to compare the changes of acute phase proteins after ketamine, thiopental and propofol anaesthesia in buffalo calves. Five calves were anaesthetized three times with ketamine, thiopental or propofol in random order at 3 weeks intervals. Calves were pre-medicated with xylazine and buterphenol. Propofol resulted in an excellent anaesthetic induction (free of excitement), short recovery times and duration of anaesthesia, whereas ketamine and thiopental produced a good and fair quality of induction respectively. Acute phase proteins showed significant increase in haptoglobin and fibrinogen, whereas albumin was significantly decreased in all groups. Haptoglobin returned to normal values 48 hours after anaesthesia with propofol and thiopental. In conclusion, the anaesthetic quality produced by propofol in buffalo calves was better compared to those of ketamine and thiopental but it has a shortThe objective of this study was to compare the changes of acute phase proteins after ketamine, thiopental and propofol anaesthesia in buffalo calves. Five calves were anaesthetized three times with ketamine, thiopental or propofol in random order at 3 weeks intervals. Calves were pre-medicated with xylazine and buterphenol. Propofol resulted in an excellent anaesthetic induction (free of excitement), short recovery times and duration of anaesthesia, whereas ketamine and thiopental produced a good and fair quality of induction respectively. Acute phase proteins showed significant increase in haptoglobin and fibrinogen, whereas albumin was significantly decreased in all groups. Haptoglobin returned to normal values 48 hours after anaesthesia with propofol and thiopental. In conclusion, the anaesthetic quality produced by propofol in buffalo calves was better compared to those of ketamine and thiopental but it has a shortduration of anaesthesia. Propofol and thiopental significantly decreased acute phase proteins due to anti-inflammatory effects.

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