The anesthesia characterized by bad quality induction with strong nervous manifestation after chloral hydrate injection. Nearly all body reflexes disappeared after propofol infusion. Complete analgesia and sedation was achieved at 4 minutes after injection where the animals showed no responses to any painful stimuli. The heart rate in this group showed gradual increase while the respiratory rate and body temperature were showed significant decrease. The recovery of the animals characterized by both of the pedal and anal reflexes appeared at 39 minutes after propofol injection .Complete recovery of the animals occurred at 95 minutes with tinny smooth recovery without any signs of nervous manifestation.