Background: the quality of the relationship between nurses and their supervisor affects their engagement to the workplace, and eliminate their intention to leave it. The study aimed to identify perceived nursing supervisor support and its relation to work engagement and turnover intention among staff nurses. Design: A Comparative correlational design was utilized to meet the aim of this study. Study setting: the study conducted at critical and non-critical care units at Benha University Hospital. The study sample composed all staff nurses (293) who are working in the above mentioned setting; 149 of staff nurses working at non-critical care units and 144 staff nurses working at critical care units. Tools: Three tools were used for data collection; Perceived nursing supervisor support questionnaire, Utrecht work engagement scale and turnover intention questionnaire. Results: less than half of staff nurses had moderate perception level regarding nursing supervisor support. Staff nurses working at critical care units had high level of work engagement than staff nurses working at non-critical care units. Staff nurses working at critical care units had high turnover intention than staff nurses working at non-critical care units. Conclusion: There was highly statistically significant positive correlation between perceived nursing supervisor support and staff nurses' work engagement at critical and non-critical care departments. Additionally, there was a highly statistically significant negative correlation between staff nurses' turnover intention, perceived nursing supervisor support and work engagement at critical and non-critical care departments. The study recommended that nursing supervisors should be trained appropriately to provide constructive feedback and adequate support to their staff nurses that help to enhance work engagement and decrease turnover intention.