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The Role of Uric Acid in Impairment of the Glomerular Filtration Rate in Non-Proteinuric Egyptian Patients with Type 2 Diabetes Mellitus

Author key words: Uric acid, e-GFR, Type 2 DM • 2015
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Publication Information
Authors Ashraf Talaat*,Elmetwally Elshahawy *,Mohamad Tantawy*,
Keywords Author key words: Uric acid, e-GFR, Type 2 DM
Journal Author key words: Uric acid, e-GFR, Type 2 DM
Publisher Not Available
Volume Not Available
Issue Not Available
Pages 1-14
publication.type International
Paper Link Not Available
Supplementary Materials Not Available
Abstract
Background: Increased uric acid levels were associated with increased risk of development of
hypertension, cardiovascular disease and progression of chronic kidney disease.
Objective: Measurement of serum uric acid(SUA), HBA1c, total cholesterol and C-reactive protein
and their relationship to the estimated GFR ( by using Cockcroft – Gault formula ).
Subjects : This cross sectional study consisted of 100 subjects (64 males and 36 Females ). To all,
history taken , anthropometric and laboratory measurements were assessed.
RESEARCH DESIGN AND METHODS :We study our patients for THE ROLE OF URIC ACID IN
IMPAIRMENT OF THE GFR IN NONPROTEINURIC PATIENTS WITH TYPE 2 DIABETES MELLITUS
Results: Our study included 100 Type 2 DM patients; range of age was 32-67 years, SUA
range was 4.4-10.3 mg/dl, e-GFR range was 42-151 ML/min.
- SUA is statistically positively correlated with the duration of DM, body weight, BMI and age (
r=0.14 P>0.05, r=0.43 P