| publication name | Aminoalkylation of nitriles by iminium ions generated in situ |
|---|---|
| Authors | Alan R. Katritzky,a,* Ashraf A. A. Abdel-Fattaha and Peter J. Steelb,* |
| year | 2006 |
| keywords | Aminoalkylation; N-(a-Aminoalkyl)benzotriazoles; b-Aminoalkyl nitriles. |
| journal | Tetrahedron Letters |
| volume | 47 |
| issue | Not Available |
| pages | 1465–1467 |
| publisher | Elsevier Ltd |
| Local/International | International |
| Paper Link | Not Available |
| Full paper | download |
| Supplementary materials | Not Available |
Abstract
Aminoalkylation of a series of primary and secondary nitriles with N-(a-aminoalkyl)benzotriazoles 1 (derived from a variety of secondary amines and aldehydes) proceeds smoothly providing the corresponding b-aminoalkyl nitriles 5a–j in 66–97% yields.