| publication name | Benzotriazole-mediated amidoalkylations of nitroalkanes, nitriles, alkynes and esters |
|---|---|
| Authors | Alan R. Katritzky,a* Ashraf A. A. Abdel-Fattaha,b, and Ilhami Celika,c |
| year | 2007 |
| keywords | Amidoalkylation, N-(β-nitroalkyl)amides, N-(β-cyanoalkyl)-amides, N-acylpropargylamines, β-N-acylamino acids |
| journal | ARKIVOC |
| volume | xi |
| issue | Not Available |
| pages | 96-113 |
| publisher | ARKAT USA, Inc. |
| Local/International | International |
| Paper Link | Not Available |
| Full paper | download |
| Supplementary materials | Not Available |
Abstract
Reactions of readily available and stable N-(α-amidoalkyl)benzotriazoles 1 (derived from a variety of aliphatic, aromatic or heterocyclic aldehydes) with diverse nitroalkanes, nitriles, alkynes and esters afforded N-(β-nitroalkyl)amides 4 (54−96%), N-(β-cyanoalkyl)amides 6 (58−88%), N-acylpropargylamines 11 (41−87%) and esters of β-N-acylamino acids 13 (68−96%), respectively.