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Expedient Acylations of Primary and Secondary Alkyl Cyanides to r-Substituted â-Ketonitriles

J. Org. Chem. • 2003
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Publication Information
Authors Alan R. Katritzky,* Ashraf A. A. Abdel-Fattah, and Mingyi Wang
Keywords Not Available
Journal J. Org. Chem.
Publisher American Chemical Society
Volume 68
Issue Not Available
Pages 4932-4934
publication.type International
Paper Link Not Available
Supplementary Materials Not Available
Abstract
Primary and secondary cyanides are efficiently acylated with N-acylbenzotriazoles 3a-f (derived
from a variety of acids) to afford the corresponding R-substituted â-ketonitriles 5a-r in 67-96%
yields.