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Expedient Synthesis of Biginelli-Type Dihydropyrimidinones Using a-(Benzotriazolyl)alkyl Urea Derivatives

SYNTHESIS • 2003
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Publication Information
Authors Ashraf A. A. Abdel-Fattah*
Keywords urea, heterocycles, pyrimidines, condensation, esters, cyclizations
Journal SYNTHESIS
Publisher Georg Thieme Verlag Stuttgart
Volume 15
Issue Not Available
Pages 2358–2362
publication.type International
Paper Link Not Available
Supplementary Materials Not Available
Abstract
Reaction of readily available a-(benzotriazolyl)alkyl
urea derivatives (derived from aromatic, heteroaromatic, and aliphatic
aldehydes) with b-keto esters resulted in 3,4-dihydropyrimidin-
2(1H)-ones in good to excellent yields.