This study was carried out during both 2018 and 2019 experimental seasons to cover the influence of the two investigated factors i.e., rootstock grape type (Freedom and Richter) and some bio-stimulants compounds (compost, Bacillus polymyxa, EM and Azotobacter chrococcum) and their possible combinations. The influence was evaluated through the response of some vegetative growth and nutritional status of the treated "Crimson" grape cultivar. The specific effect of rootstock type on vegetative growth, data revealed that, Freedom rootstock was better than the other investigated rootstock (Richter) in this respect. Also, fertilizer with T4 and T5 g/transplant were superiors in this respect whereas able to they were increase significantly vegetative growth as compared with the other different investigated fertilization during both 2018 and 2019 seasons of study. Considering the interaction effect of the two investigated factors i.e., rootstock type and different bio-stimulants (compost, Bacillus polymyxa, EM and Azotobacter chrococcum) on vegetative growth of grape transplants, data show the highest value of vegetative growth were obtained with the combination between Crimson grape transplants grafted on Freedom rootstock and fertilized with T4, T5 and T7 g/transplants. The obtained results clearly show that, all treatments increased nutritional status for both rootstocks (Freedom and Richter) of grapevine (Vitis vinifera L.) in leaves as compared with control treatment.